长期补钙对儿童血压的影响

55名4～5岁健康儿童分两组（A组34名，平均4.45±0．5岁；B组21名，平均4岁）进行长期口服补钙的自身交叉对比试验，结果显示两组儿童补钙前后各自的平均24h尿钙排泄量均无显著变化，未提供补钙对儿童血压影响的证据。本研究提示尿钠、钠／钾的增加对血压水平的升高有显著影响。

Effect of Long-term Oral Calcium Supplementation on Blood Pressure in Children

Fifty-five cases aged 4~5 year old healthy children were divided into two groups. group A (n = 34 ) male 16.female 18, and group B (n = 21 ), male 8. female 13. Bothgroups took conventional diet and blood pressure, height.weight and heart rate were measured, 24 hour urine was collected for measuring Na,K,Ca and creatininc. During the first6 months, group A took a diet with sodium restricted to 50mmol and calcium gluconate 1. 5 g per day. Group B took regular diet without sodium restriction and calcium supplernent.The above examinations were repeated after six months, then,the diet pattern crossed over, and followed for another 6months and the examinations were repeated at the end of investigation. It was shown that the SBP. DBP, mean BP ingroup A were significantly decreased after 6 months sodium restriction and calcium supplementation. but BP restored to evenhigher level after 6 months regular diet. In group B when urinary sodium was stable, the calcium supplementation did notproduce any BP lowering effect. No difference in urinary calcium excretion in either group during the whole study period hadbeen found.