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多发性骨髓瘤的临床及全身磁共振分析
引用本文:刘许慧,袁梅,秦斌,王德杭. 多发性骨髓瘤的临床及全身磁共振分析[J]. 医学影像学杂志, 2011, 21(1): 98-102
作者姓名:刘许慧  袁梅  秦斌  王德杭
作者单位:南京医科大学第一附属医院放射科,江苏,南京,210029
摘    要:
目的:分析多发性骨髓瘤的临床特征及其全身磁共振表现,探讨全身磁共振分期与临床分期之间的关系。方法:采用Siemens 3.0T磁共振对15例经病理证实的多发性骨髓瘤患者进行全身检查。采用Fisher精确概率法对磁共振及临床两种分期方法进行分析。结果:多发性骨髓瘤最常见的临床表现有骨痛、贫血、乏力、肝脾肿大和浅表淋巴结肿大等;15例患者中全身磁共振表现为正常型4例,弥漫型3例,局灶型3例,混合型4例,胡椒面型1例。磁共振分期为Ⅰ期4例,Ⅱ期3例,Ⅲ期8例,临床分期为Ⅰ期1例,Ⅱ期4例,Ⅲ期10例。两种分期方法进行统计学分析得出P=0.46>0.05。结论:多发性骨髓瘤临床表现多样化,主要表现为骨痛;全身磁共振成像对于多发性骨髓瘤具有较好的成像效果和评估价值;两种分期方法之间没有统计学差异。

关 键 词:多发性骨髓瘤  全身磁共振成像

The clinic and whole-body analysis of multiple myeoma by MRI
LIU Xu-hui,YUAN Mei,QIN Bin,WANG De-hang. The clinic and whole-body analysis of multiple myeoma by MRI[J]. Journal of Medical Imaging, 2011, 21(1): 98-102
Authors:LIU Xu-hui  YUAN Mei  QIN Bin  WANG De-hang
Affiliation:LIU Xu-hui,YUAN Mei,QIN Bin,WANG De-hang Department of Radiology,The First Affiliated Hospital of Nanjing Medical University,Nanjing 210029,P.R.China
Abstract:
Objective:To analyze the clinical manifestations of multiple myeloma and the images of whole-body magnetic resonance,to explore the relationship between MRI stage and clinical stage.Methods:15 multiple myeloma patients enrolled.Histological proof of multiple myeloma was obtained in all cases.Fisher exact test is used to analyze MRI stage and clinical stage.Results:The most common clinical manifestations of multiple myeloma are bone pain,fatigue,anemia,and hepatosplenomegaly and superficial lymphadenopathy.1...
Keywords:Whole-body magnetic resonance(WB MR)  Multiple myeloma(MM)  
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