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肾动脉狭窄的肾脏CT血流灌注参数研究
引用本文:何悦明,郑爽爽,杨振涛,王青. 肾动脉狭窄的肾脏CT血流灌注参数研究[J]. 医学影像学杂志, 2011, 21(1): 85-88
作者姓名:何悦明  郑爽爽  杨振涛  王青
作者单位:1. 首都医科大学附属复兴医院,放射科,北京,100038
2. 首都医科大学附属复兴医院,内科,北京,100038
摘    要:目的:探讨利用CT血流灌注参数研究肾动脉狭窄患者肾脏血流状况。方法:高血压患者36人,分为肾动脉狭窄组(24人)和对照组(12人),进行肾脏CT电影扫描获得动态序列图像,通过AW影像工作站计算肾脏皮质血流灌注参数,分析肾脏皮质血流灌注与肾动脉狭窄的关系。结果:肾动脉狭窄>75%组肾皮质单位体积血流量(BF)(189.9±102.3ml/100g/min)低于对照组(308.4±99.9ml/100g/min),有显著差异(P=0.026)。肾动脉狭窄50%-75%组及狭窄>75%组肾皮质微血管容积(BV)(24.6±7.6ml/100g,21.4±12.6ml/100g)低于对照组(41.1±14.1ml/100g),有非常显著差异(P=0.008,0.001)。各组之间平均通过时间(MTT)、毛细血管表面通透性(PS)无显著性差异(P>0.05)。结论:明显肾动脉狭窄的肾脏皮质BF、BV下降,CT血流灌注参数可以为评估肾动脉狭窄的肾脏是否缺血提供帮助。

关 键 词:肾动脉狭窄  灌注  体层摄影术,X线计算机

Research of renal perfusion patterns with dynamic contrast-enhanced CT in patients with renal artery stenosis
HE Yue-ming,ZHENG Shuang-shuang,YANG Zhen-tao,WANG Qing. Research of renal perfusion patterns with dynamic contrast-enhanced CT in patients with renal artery stenosis[J]. Journal of Medical Imaging, 2011, 21(1): 85-88
Authors:HE Yue-ming  ZHENG Shuang-shuang  YANG Zhen-tao  WANG Qing
Affiliation:HE Yue-ming1,ZHENG Shuang-shuang1,YANG Zhen-tao1,WANG Qing2 1.Radiology Department,Fuxing Hospital of the Capital University of Medical Sciences,Beijing 100038,P.R.China 2.Medicine Department,Fuxing Hospital of the Capital University of Medical Scieuces,P.R.China
Abstract:Objective:The purpose of our study was to assess the potential value of the renal parameters measured by perfusion CT in patients with renal artery stenosis.Methods:36 patients(24 patients with renal artery stenosis and 12 control subjects) were performed dynamic computed tomography.Perfusion parameters,blood flow(BF),blood volume(BV),mean transit time(MTT),permeability-surface(PS) were sampled in the renal cortex area and determined the association with renal artery stenosis.Results:Patients with serious r...
Keywords:Renal artery stenosis  Perfusion  Computed tomography(CT)  
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