无创呼吸机治疗慢性阻塞性肺疾病合并呼吸衰竭患者临床研究

目的 研究无创呼吸机治疗慢性阻塞性肺疾病(慢阻肺)合并呼吸衰竭的临床效果. 方法 整群选取2013年1月—2014年7月该院接诊的慢阻肺并呼吸衰竭患者50例,随机分为观察组(加用无创呼吸机治疗)与对照组(常规治疗) 各25例, 比较两组临床疗效. 结果 观察组的PaCO2与1年复发率均明显低于对照组 (t=13.47,x2=9.10;P<0.05),且观察组的PaO2、HR与治疗有效率则相对更高,组间差异有统计学意义(t=14.38,9.74,x2=8.32;P<0.05). 结论 无创呼吸机治疗慢阻肺并呼吸衰竭的效果确切,可推广使用.

Clinical Study of the Effect of Non-invasive Ventilation in the Treatment of Chronic Obstructive Pulmonary Disease with Respiratory Failure

Objective To study the clinical results of non-invasive ventilation in the treatment of chronic obstructive pul-monary disease (COPD) with respiratory failure. Methods 50 cases with COPD and respiratory failure admitted in our hospi-tal from January 2013 to December 2014 were selected and randomly divided into two groups, the observation group and the control group with 25 cases in each. Patients in the observation group were treated by non-invasive ventilation, while those in the control group were treated by the conventional treatment. And the clinical efficacy of the two groups was compared. Results The PaCO2 level and 1-year recurrence rate of the observation group was significantly lower than that of the control group, respectively(t=13.47, x2=9.10;P<0.05). The PaO2 level, HR and treatment effect of the observation group was relatively higher than the control group with statistically significant difference(t=14.38,9.74, x2=8.32; P<0.05). Conclusion Non-inva-sive ventilation has exact effect in the treatment of chronic obstructive pulmonary disease and respiratory failure, which can be widely promoted.