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| 羟基喜树碱膀胱灌注预防浅表性膀胱癌术后复发 | |
| 引用本文： | 韩杰,王章才,姜书传,杨维娟,董昌斌,卓栋,黄群联,黄后宝,程庆水. 羟基喜树碱膀胱灌注预防浅表性膀胱癌术后复发[J]. 皖南医学院学报, 2003, 22(3): 197-198 |
| 作者姓名： | 韩杰 王章才 姜书传 杨维娟 董昌斌 卓栋 黄群联 黄后宝 程庆水 |
| 作者单位： | 附属弋矶山医院泌尿外科,241001 |
| 摘 要： | 目的 研究羟基喜树碱膀胱灌注预防浅表性膀胱癌术后复发的疗效。方法 对 13例浅表性膀胱癌术后的患者采用羟基喜树碱 10mg溶于 30ml生理盐水中膀胱灌注 ,每周一次 ,连续 10周 ;每两周一次 ,连续 10周 ;以后每月一次 ,维持 2～ 3年。结果 1年内复发 1例 ,2年内复发 1例 ,11例 3年以上无复发。结论 羟基喜树碱用于浅表性膀胱肿瘤术后的膀胱灌注疗效确切 ,且副作用少而轻。今后应对其药代动力学作进一步研究 |
| 关 键 词： | 膀胱癌 羟基喜树碱 术后复发 |
| 文章编号： | 1002-0217(2003)03-0197-02 |
| 修稿时间： | 2003-01-28 |
Intravesical instillation of HCPT as a prevention of postoperative recurrence of the superficial bladder cancer |
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| Han jie,Wang Zhangcai,Jiang Shuchuan,et al. Intravesical instillation of HCPT as a prevention of postoperative recurrence of the superficial bladder cancer[J]. Acta Academiae Medicinae Wannan, 2003, 22(3): 197-198 | |
| Authors: | Han jie Wang Zhangcai Jiang Shuchuan et al |
| Abstract: | Objective To study the efficacy of intravesical instillation of HCPT for prevention of postoperative recurrence of superficial bladder cancer.Methods 13 cases of postoperative superficial bladder cancer were treated with HCPT 10mg dissolved in 30ml normal saline,once a week for 10 weeks,twice a week for 10 weeks and subsequently once a month for 2～3 years.Results There was 1 case of recurrence within the first year,1 case recurrence within the second year,11 cases without recurrence in three years.Conclusion Intravesical instillation of HCPT can effectively prevent postoperative recurrence of superficial bladder cancer with less side effects.Further study of pharmacokinetics of HCPT is necessary. |
| Keywords: | bladder cancer HCPT postoperation recurrence |
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