我院耐甲氧西林金黄色葡萄球菌的耐药性及肠毒素分析 |
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引用本文: | 陈欣,张雅莲.我院耐甲氧西林金黄色葡萄球菌的耐药性及肠毒素分析[J].中华整形烧伤外科杂志,1997,13(5):377-379. |
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作者姓名: | 陈欣 张雅莲 |
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摘 要: | 收集了我院1994年10月至1995年4月金黄色葡萄球菌100株,应用药敏试验筛选MRSA,并检测其对12种抗生素的耐药性,计算MIC50和MIC90,应用乳胶凝集试验法,测定其肠毒素产生率。结果我院总的MRSA阳性率为60%,烧伤科的MRSA的阳性率为67.4%,内科62.5%,骨科44.5%,MRSA耐药性低于50%的有万古霉素(3.3%)去甲万古霉素(5%),丁胺卡那霉素(21.5%)3种,
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关 键 词: | 甲氧西林 金黄色葡萄球菌 肠毒素 耐药性 |
Analysis of antibiotic resistance and production of enterotoxin of MRSA] |
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Authors: | X Chen Y Zhang Y Sun |
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Institution: | Beijing Jishuitan Hospital. |
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Abstract: | 100 separate Staphylococcus aureus (S. a) isolates at Beijing Jishuitan Hospital during Oct. 1994-Apr. 1995 were submitted to determine the proportion of methicillin-resistant S. a (MRSA) and susceptibility test to 12 antibiotics. MIC determinations of the antibiotics were performed. Also, production rate of enterotoxin was measured with RPLA method. The results showed that MRSA constituted 60% of all cultures. (Burns Dept. 67.4%, Internal Medicine 62.5%, Orthopedics Dept. 44%). The antibiotics with resistant rate of MRSA below 50% included vancomyin (3.3%), norvancomyin (5%) and amikacin (21.5%). The production rate of enterotoxin was 100% in MRSA and 20% in MSSA (methicillin-sensitive S. a). In this group, 35% of MRSA and 5% of MSSA produced more than 2 types of enterotoxin. |
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