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男性不育者精子顶体酶活性影响因素分析
引用本文:刘睿智,沙艳伟,许宗革,董乃屹,辛暨丽,李哲,王忠山. 男性不育者精子顶体酶活性影响因素分析[J]. 吉林大学学报(医学版), 2003, 29(5): 567-569
作者姓名:刘睿智  沙艳伟  许宗革  董乃屹  辛暨丽  李哲  王忠山
作者单位:吉林大学基础医学院细胞生物学教研室,吉林,长春,130021;吉林省计划生育研究所
基金项目:吉林省计委资助项目;1999;
摘    要:目的 :分析某些因素对男性不育者精子顶体酶活性的影响。方法 :分光光度比色法检测3767例男性不育者精子顶体酶活性。结果 :精液液化时间延长组、p H值降低组、白细胞数 >5个 /HP组的精子顶体酶活性均显著低于其相应对照组 ( P<0 .0 0 1 ,P<0 .0 0 1 ,P<0 .0 5 )。顶体酶活性与支原体感染和精浆 As Ab无关 ( P>0 .0 5 ,P>0 .0 5 )。结论 :精液液化时间、p H值和白细胞数影响顶体酶活性 ,精液支原体感染和精浆 As Ab对顶体酶活性无影响

关 键 词:不育  男性/酶学  精子/酶学  顶体蛋白酶/分析  支原体感染/并发症  解脲脲原体  抗精子抗体
文章编号:1671-587X(2003)05-0567-03
修稿时间:2002-07-10

Analysis of Influence Factors of Human Sperm Acrosin Activity
Abstract:Objective:In order to study the influence factor of the sperm acrosin activity. Methods:The sperm acrosin activities in 3 767 male infertiles were determined and the influence factors were analyzed. Results:There was a significant difference in normal semen liquefied duration, pH and white blood cells (WBC) under microscope ( P <0.001, P <0.001, P <0.05). The comparison between U.urealyticum negative group and U.urealyticum positive group showed that the acrosin activity was not significant difference ( P >0.05). The comparison between AsAb positive group and AsAb negative group showed the acrosin activity was not significant difference ( P >0.05).Conclusion:Semen liquefied duration, pH and WBC could affect acrosin activity. U.urealyticum infection in semen and AsAb in seminal plasma could not affect acrosin activity. [
Keywords:Infertility   male/enzyme  Sperm/enzyme  Arosin/analysis  U.urealyticum infection/complication  Antisperm antibody
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