男性不育者精子顶体酶活性影响因素分析 |
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引用本文: | 刘睿智,沙艳伟,许宗革,董乃屹,辛暨丽,李哲,王忠山. 男性不育者精子顶体酶活性影响因素分析[J]. 吉林大学学报(医学版), 2003, 29(5): 567-569 |
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作者姓名: | 刘睿智 沙艳伟 许宗革 董乃屹 辛暨丽 李哲 王忠山 |
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作者单位: | 吉林大学基础医学院细胞生物学教研室,吉林,长春,130021;吉林省计划生育研究所 |
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基金项目: | 吉林省计委资助项目;1999; |
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摘 要: | 目的 :分析某些因素对男性不育者精子顶体酶活性的影响。方法 :分光光度比色法检测3767例男性不育者精子顶体酶活性。结果 :精液液化时间延长组、p H值降低组、白细胞数 >5个 /HP组的精子顶体酶活性均显著低于其相应对照组 ( P<0 .0 0 1 ,P<0 .0 0 1 ,P<0 .0 5 )。顶体酶活性与支原体感染和精浆 As Ab无关 ( P>0 .0 5 ,P>0 .0 5 )。结论 :精液液化时间、p H值和白细胞数影响顶体酶活性 ,精液支原体感染和精浆 As Ab对顶体酶活性无影响
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关 键 词: | 不育 男性/酶学 精子/酶学 顶体蛋白酶/分析 支原体感染/并发症 解脲脲原体 抗精子抗体 |
文章编号: | 1671-587X(2003)05-0567-03 |
修稿时间: | 2002-07-10 |
Analysis of Influence Factors of Human Sperm Acrosin Activity |
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Abstract: | Objective:In order to study the influence factor of the sperm acrosin activity. Methods:The sperm acrosin activities in 3 767 male infertiles were determined and the influence factors were analyzed. Results:There was a significant difference in normal semen liquefied duration, pH and white blood cells (WBC) under microscope ( P <0.001, P <0.001, P <0.05). The comparison between U.urealyticum negative group and U.urealyticum positive group showed that the acrosin activity was not significant difference ( P >0.05). The comparison between AsAb positive group and AsAb negative group showed the acrosin activity was not significant difference ( P >0.05).Conclusion:Semen liquefied duration, pH and WBC could affect acrosin activity. U.urealyticum infection in semen and AsAb in seminal plasma could not affect acrosin activity. [ |
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Keywords: | Infertility male/enzyme Sperm/enzyme Arosin/analysis U.urealyticum infection/complication Antisperm antibody |
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