| 绝经早期低剂量激素治疗对乳腺的影响分析 |
| |
| 引用本文： | 龚莉莉,张绍芬,纪律,徐阳,周毓青. 绝经早期低剂量激素治疗对乳腺的影响分析[J]. 实用妇产科杂志, 2009, 25(2) |
| |
| 作者姓名： | 龚莉莉 张绍芬 纪律 徐阳 周毓青 |
| |
| 作者单位： | 复旦大学附属妇产科医院,上海,200011 |
| |
| 摘 要： | 目的:研究绝经早期低剂量激素治疗(HT)对乳腺的影响.方法:收集绝经早期妇女104例,随机分为激素组和中药组各52例,治疗1年,每3个月随访1次,由专人进行绝经期生存质量量表评分,受试者每日记录乳房胀痛情况.结果:绝经期生存质量量表中,激素组用药前评分为1.90±0.94分,用药后3月,6月,9月,12月评分较前均有显著性下降,分别为1.27±0.67分,1.08±0.62分,0.97±0.64分,0.69±0.50分;中药组用药后3月,6月,9月,12月评分也较用药前有显著性下降.激素组在用药3月,6月,9月,12月的乳房胀痛发生率分别为29.17%.14.63%,22.22%,9.09%,各时间点与中药组相比差异无统计学意义;在用药1～3月,激素组乳房胀痛程度为中度或重度的受试者占35.7%,显著多于中药组0%,其余各时间点两组在乳房胀痛程度上无统计学意义;激素组用药前乳腺小叶增生发生率为60%,用药后为91.4%,用药前后差异有统计学意义.结论:绝经早期低剂量HT和中药治疗1年均能有效提高生存质量,HT使乳腺小叶增生发生率增加,应用HT的过程中应加强乳房监测.
|
| 关 键 词： | 绝经早期 激素治疗 乳腺 生存质量 |
Effect of Low-dose Hormone Therapy on Breast at the Early Stage of Menopause |
| |
| GONG Lili,ZHANG Shaofen,JI Lv,et al. Effect of Low-dose Hormone Therapy on Breast at the Early Stage of Menopause[J]. Journal of Practical Obstetrics and Gynecology, 2009, 25(2) |
| |
| Authors: | GONG Lili ZHANG Shaofen JI Lv et al |
| |
| Affiliation: | Obstetrics & Gynecology Hospital of Fudan University;Shanghai 200011;China |
| |
| Abstract: | Objective:To study the effect of low-dose hormone therapy(HT) on breast at the early stage of menopause in women.Methods:A total of 104 perimenopausal women were enrolled in this trial.They were randomly divided into hormone group(HG) and Chinese traditional medicine group(CG).52 cases were in each group and given therapy for 1 year.Mammary swelling pain was recorded everyday by patient.Follow-up was 3 months,and scales of Menopause Specific Life Quality were scored by specialist.Results:In the scales of Me... |
| |
| Keywords: | |
| 本文献已被 CNKI 万方数据 等数据库收录！ |
|
