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| 复方酮康唑软膏的制备及临床应用 | |
| 引用本文： | 何光明,施震,孟君,罗顺德. 复方酮康唑软膏的制备及临床应用[J]. 中国医院药学杂志, 2001, 21(11): 663-665 |
| 作者姓名： | 何光明 施震 孟君 罗顺德 |
| 作者单位： | 1. 北京大学深圳医院,广东深圳,518036 2. 武汉大学人民医院,湖北,武汉,430060 |
| 摘 要： | 目的：复方酮康唑软膏的制备和临床应用。方法：采用二阶导数光谱法和单波长法分别测定酮康唑与依诺沙星的含量。结果：被测组分的平均回收率和相对标准偏差分别为：酮康唑101．6％和0．85％，依诺沙星100．2％和0．26％。结论：方法简便，结果准确，可用于复方酮康唑软膏的质量控制。 |
| 关 键 词： | 复方酮康唑软膏 二阶导数光谱法 酮康唑 依诺沙星 质量控制 皮肤药 |
| 文章编号： | 1001-5213(2001)11-0663-03 |
| 修稿时间： | 2001-04-18 |
Preparation and clinical application of compound ketoconazole ointment |
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| HE Guang-Ming,SHI Zen,MENG Jun,et al. Preparation and clinical application of compound ketoconazole ointment[J]. Chinese Journal of Hospital Pharmacy, 2001, 21(11): 663-665 | |
| Authors: | HE Guang-Ming SHI Zen MENG Jun et al |
| Abstract: | OBJECTIVE To prepare the compound ketoconazole ointment and observe the effects on skin infection. METHODS The second order devivative spectrophotometry and ultraviolet spectrophotometry were used to determinate ketoconazole and enoxacin in respectively ointment.RESULTS The average recoveries and relative SD were 101.6% , 0.85% for ketoconazole and 100.2% , 0.26% for enoxacin. CONCLUSIONS The method was simple and accurate, and could be used for the quality control of compound ketoconazole ointment. |
| Keywords: | compound ketoconazole ointment second derivative spectrophotometry ketoconazole enoxacin |
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