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Development of a spray-drying method for the formulation of respirable microparticles containing ofloxacin–palladium complex
Authors:Francesco Palazzo  Stefano GiovagnoliAurelie Schoubben  Paolo BlasiCarlo Rossi  Maurizio Ricci
Institution:Department of Chemistry and Technology of Drugs, Università degli Studi di Perugia, Via del Liceo 1, 06123 Perugia, Italy
Abstract:The purpose of this study was to produce low-releasing spray-dried polymeric microparticles (MP) useful to target alveolar macrophages in tuberculosis (TB) inhalation therapy.
Keywords:Ofloxacin&ndash  palladium complex  Spray drying  Microparticles  D-optimal design  Low release
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