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| Inhibitory Effect of Cantharidin on Proliferation of A549 Cells | |
| 引用本文： | 王晓华,尹元琴,隋承光,孟凡东,马萍,姜又红. Inhibitory Effect of Cantharidin on Proliferation of A549 Cells[J]. 中国癌症研究, 2007, 19(4): 283-286. DOI: 10.1007/s11670-007-0283-2 |
| 作者姓名： | 王晓华 尹元琴 隋承光 孟凡东 马萍 姜又红 |
| 作者单位： | Cancer Research Institute First Affiliated Hospital，China Medical University，Cancer Research Institute，First Affiliated Hospital，China Medical University，Cancer Research Institute，First Affiliated Hospital，China Medical University，Cancer Research Institute，First Affiliated Hospital，China Medical University，Cancer Research Institute，First Affiliated Hospital，China Medical University，Cancer Research Institute，First Affiliated Hospital，China Medical University，Shenyang 110001，Shenyang 110001，Shenyang 110001，Shenyang 110001，Shenyang 110001，Shenyang 110001 |
| 摘 要： | Objective:To study the inhibition of Cantharidin against the proliferation of human lung cancer A549 cells and its mechanism.Methods:MTT assay was employed to determine the inhibition of Cantharidin against proliferation of A549 cells and flow Cytometry was applied to analyze A549 cell cycle and the effect of Cantharidin on cell cycle.Results:Cantharidin showed inhibition against the proliferation of A549 cells,and the inhibition was mediated by blocking A549 cell cycle at G2/M phase significantly.Conclusion:Cantharidin exhibits inhibition against the proliferation of human lung cancer A549 cells. |
| 关 键 词： | 肺癌 肿瘤 治疗方法 细胞 繁殖速度 |
| 文章编号： | 1000-9604（2007）-04-04-0282 |
| 收稿时间： | 2007-07-31 |
| 修稿时间： | 2007-09-25 |
Inhibitory effect of Cantharidin on proliferation of A549 cells |
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| Wang Xiao-hua,Yin Yuan-qin,Sui Cheng-guang,Meng Fan-dong,Ma Ping,Jiang You-hong. Inhibitory effect of Cantharidin on proliferation of A549 cells[J]. Chinese Journal of Cancer Research, 2007, 19(4): 283-286. DOI: 10.1007/s11670-007-0283-2 | |
| Authors: | Wang Xiao-hua Yin Yuan-qin Sui Cheng-guang Meng Fan-dong Ma Ping Jiang You-hong |
| Affiliation: | (1) Cancer Research Institute, First Affiliated Hospital, China Medical University, Shenyang, 110001, China |
| Abstract: | Objective:To study the inhibition of Cantharidin against the proliferation of human lung cancer A549 cells and its mechanism.Methods:MTT assay was employed to determine the inhibition of Cantharidin against proliferation of A549 cells and flow Cytometry was applied to analyze A549 cell cycle and the effect of Cantharidin on cell cycle.Results:Cantharidin showed inhibition against the proliferation of A549 cells,and the inhibition was mediated by blocking A549 cell cycle at G2/M phase significantly.Conclusion:Cantharidin exhibits inhibition against the proliferation of human lung cancer A549 cells. |
| Keywords: | Cantharidin(CTD) Inhibition Human lung cancer cells A549 |
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