Tau gene and Parkinson's disease: a case-control study and meta-analysis |
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Authors: | Healy D G Abou-Sleiman P M Lees A J Casas J P Quinn N Bhatia K Hingorani A D Wood N W |
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Affiliation: | Department of Molecular Neuroscience, Institute of Neurology, Queen Square, London, UK. |
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Abstract: | OBJECTIVE: To investigate whether the tau H1 haplotype is a genetic risk factor in Parkinson's disease and to report a meta-analysis on all previously published data METHODS: and results: In a sample of 580 patients with Parkinson's disease and 513 controls there was an increased risk of Parkinson's disease for both the tau H1 haplotype (p
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