Cyclin D1 amplification and expression in human breast carcinoma: correlation with histological prognostic markers and oestrogen receptor expression |
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| Authors: | S D Worsley B A Jennings K H Khalil M Mole A C Girling |
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| Affiliation: | Molecular Genetics Department, Norfolk and Norwich NHS Healthcare Trust, Brunswick Road, Norwich NR1 3SR;Department of Surgery;Histopathology Department |
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| Abstract: | Aims—To study the amplification of the Cyclin D1 gene (CCND1) in human breast carcinoma; to relate this to Cyclin D1 protein expression; to relate these parameters to recognised pathological prognostic factors, including oestrogen receptor (ER) status. |
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