Enhanced growth hormone response to clonidine after repeated electroconvulsive shock in a primate species |
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| Authors: | J.R. McWilliam B.S. Meldrum S.A. Checkley |
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| Affiliation: | Department of Neurology & Department of Psychiatry, Institute of Psychiatry, de Crespigny Park, London SE5 8AF, U.K. |
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| Abstract: | (1) The plasma growth hormone response to clonidine, 0.02 mg/kg, i.v., is enhanced 15 days after a course of 7 electroconvulsive shocks (ECS) in baboons, Papio papio. (2) This supports the hypothesis, based on behavioural observations in rodents, that the therapeutic action of electroconvulsive treatment (ECT) in depressive illness is associated with enhanced responses to monoamines. |
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| Keywords: | Clonidine growth hormone ECS brain monoamines |
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