|
|||||
|
|
| 苯佐卡因凝胶剂药效学实验研究 | |
| 引用本文： | 周卫,吴晓兰. 苯佐卡因凝胶剂药效学实验研究[J]. 药学与临床研究, 2000, 8(4): 7-9 |
| 作者姓名： | 周卫 吴晓兰 |
| 作者单位： | 江苏省药物研究所南京210009 |
| 摘 要： | 将苯佐卡因制成以卡波姆为基质的外用凝胶剂，进行了药效学实验、口腔粘膜刺激性实验和急性毒性实验。结果表明苯佐卡因凝胶药效明显，与对照组有显差异；使用后口腔粘膜未见刺激性；口服及腹腔注射LD50分别为1327．9mg／kg及1222．6mg／kg。 |
| 关 键 词： | 苯佐卡因 凝胶剂 制备工艺 药效学试验 急性毒性试验 卡波姆 局部麻醉药 |
| 收稿时间： | 2000-03-03 |
Study on Preparation of Benzocain Gel and Its Pharmacodynamics |
|
| Zhou Wei and Wu Xiaolan. Study on Preparation of Benzocain Gel and Its Pharmacodynamics[J]. Pharmacertical and Clinical Research, 2000, 8(4): 7-9 | |
| Authors: | Zhou Wei and Wu Xiaolan |
| Abstract: | This paper introduces the preparation of a topic gel- Benzocain gel made using carbomer 934P. The results of pharmacodynamics show that its effects are obvious and the LD50 are 1327.9 mg/kg(po) and 1222. 6 mg/kg(ip). |
| Keywords: | Benzocain Gel Preparation Pharmacodynamics LD50 |
| 本文献已被 维普 等数据库收录！ | |
| 点击此处可从《药学与临床研究》浏览原始摘要信息 | |
| 点击此处可从《药学与临床研究》下载全文 | |