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Results of a double blind study of 89-strontium therapy of skeletal metastases of prostatic carcinoma |
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| Authors: | Klaus Buchali Hans-Jacob Correns Michael Schuerer Dietmar Schnorr Hildegard Lips Karin Sydow |
| Institution: | (1) Klinik für Nuklearmedizin, Bereich Medizin (Charitè), Humboldt-Universität, Schuhmannstrasse 20/21, 1000 Berlin, German Democratic Republic;(2) Klinik für Urologie, Bereich Medizin (Charitè), Humboldt-Universität, Schuhmannstrasse 20/21, 1000 Berlin, German Democratic Republic |
| Abstract: | Forty-nine patients were treated with either 3×75 MBq 89Sr or saline as placebo. Analysis of results 1 to 3 years after therapy revealed the ineffectiveness of 89Sr to relieve pain from metastases. Unexpectedly, a higher survival rate was found after Sr application (46% vs 4% after 2 years). Covariate analysis underlines the effect of 89Sr therapy on life expectation. |
| Keywords: | Radionuclide therapy Skeletal metastases 89-strontium |
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