非酒精性脂肪肝中医患者报告结局量表的性能测评研究

目的 按国际患者报告结局(Patient reported outcomes,PRO)量表研制规范,从信度、效度两方面评价非酒精性脂肪肝(NAFLD)中医PRO量表的科学性能.方法 临床纳入200例NAFLD患者,发放NAFLD中医PRO量表,并汇总数据结果.分别通过克朗巴赫系数(cronbach's alpha)法、...

Study on Performance Evaluation of Chinese Medicine Patient Reporting Outcome Scale for Nonalcoholic Fatty Liver Disease

Objective:To evaluate the scientific performance of Chinese medicine PRO scale for nonalcoholic fatty liver disease(NAFLD)in terms of reliability and validity according to the development standard of the international patient reported outcomes(PRO)scale.Methods:200 cases of NAFLD patients were included in the study.NAFLD TCM Pro scale was issued,and the data results were summarized.Cronbach’s alpha method and split half reliability method were used to evaluate the internal consistency reliability and split half reliability of the scale,so as to evaluate the reliability of the scale;correlation coefficient method and factor analysis method were used to evaluate the content validity and structural validity of the scale,so as to evaluate the validity of the scale.Results:198 copies of the scale were recycled and the recycle rate was 99%.Whole Cronbach’sαcoefficient of NAFLD TCM Pro scale was 0.903,and the scores of physiology,psychology and treatment were 0.862,0.682 and 0.617 respectively,all of which were greater than 0.6,which indicated the qualified internal consistency reliability;the whole Spearman Brown coefficient of the scale was 0.864,greater than 0.6,and the three domains of physiology,psychology and treatment were 0.862,0.659 and 0.497 respectively.Except the treatment field,all had qualified split half reliability;Spearman coefficients of all items and domains were greater than 0.2,and P<0.01,indicating that the scale had good content validity;factor analysis showed that 61.858%of the variables could be explained by common factors,which indicated that the scale had good structural validity.Conclusion:NAFLD TCM PRO scale has good reliability and validity,and has certain reliability and effectiveness,which can be used in the clinical efficacy evaluation of traditional Chinese medicine treatment of NAFLD.