广西地区低出生体重儿危险因素分析

目的 分析广西地区低出生体重的危险因素,为制定低出生体重干预措施提供依据.方法 本研究为多中心横断面回顾性统计分析研究,以2018年广西大部分地区新生儿为研究对象,病例组共纳入37010例(占总数91.31％)低出生体重活产儿,对照组随机抽取54677例正常出生体重活产儿,采用孕产妇个案调查表收集相关孕产妇数据及新生儿...

Risk factors analysis for low-birth-weight infants,Guangxi area

Objective To analyzerisk factors for low-birth-weight infant (LBWI) so as to provide basis for making intervention policies of LBWI.Methods 37010 (91.31%) low birth weight live births were included as case group and 54677 normal birth weight infants were included as control group. Pregnant women and infants’ data were collected using case questionnaire. The risk factors were analyzed by univariate analysis and multivariate logistic regression analysis.Results Univariate analysis showed the gender,infants’birth body length, nationality, gestational age, multiple pregnancy, birth defect, birth process time, gestation weeks for the first exam, the frequency of being examined during pregnancy, gravidity, parity, postpartum hemorrhage and hemoglobin, diastolic blood pressure, gravida weight and folic acid taking prior to gestation 13 weeks of LBWI were significant different from the data of control group (P<0.001). Suspicious risk factors (P<0.1 in univariate analysis) were included into the multivariate logistic regression analysis. The results showed the gender (OR:1.345,95%CI:1.278-1.415), infants’birth body length (OR:0.250,95%CI:0.244-0.255), rural residents (OR:1.119,95%CI:1.037-1.208), gravidity (OR:0.938,95%CI:0.916-0.960), parity (OR:0.859,95%CI:0.825-0.894), gestational age (OR:0.587,95%CI:0.576-0.598), birth defect (OR:1.627,95%CI:1.304-2.031), the frequency of being examined during pregnancy (OR:0.959,95%CI:0.951-0.967), multiple pregnancy (OR:3.268,95%CI:2.838-3.765) , diastolic blood pressure prior to gestation 13 weeks (OR:1.003,95%CI:1.000-1.006), gravida weight prior to gestation 13 weeks (OR:0.989,95%CI:0.986-0.992) and folic acid taking prior to gestation 13 weeks (OR:0.936,95%CI:0.891-0.985) were risk factors of LBWI.Conclusion Strengthening health education,perinatal health care management, birth defects screening, regular prenatal examinationsand nutrition turnover during pregnancy might be helpful to reduce LBWI incidence.