Quantification of Clostridium difficile in antibiotic-associated-diarrhea patients |
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Authors: | Naaber Paul Stsepetova Jelena Smidt Imbi Rätsep Merle Kõljalg Siiri Lõivukene Krista Jaanimäe Liis Löhr Iren H Natås Olav B Truusalu Kai Sepp Epp |
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Affiliation: | Department of Medical Microbiology, Stavanger University Hospital, Postbox 8100, 4068 Stavanger, Norway. napa@sus.no |
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Abstract: | Comparing culture- and non-culture-based methods for quantifying Clostridium difficile in antibiotic-associated-diarrhea patients, we found that the real-time PCR method correlated well with quantitative culture and was more sensitive. A positive association between the population levels of C. difficile and the presence of its toxins was found. |
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