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白藜芦醇衍生物及类似物的研究进展
引用本文:陈国良,耿春梅,刘湘永. 白藜芦醇衍生物及类似物的研究进展[J]. 药学进展, 2006, 30(4): 145-150
作者姓名:陈国良  耿春梅  刘湘永
作者单位:沈阳药科大学制药工程学院,辽宁,沈阳,110016
基金项目:国家自然科学基金;中国科学院资助项目
摘    要:
分类综述白藜芦醇衍生物和类似物的生理药理活性及其构效关系,其中包括羟基类似物及甲基化和酯类衍生物等。白藜芦醇衍生物和类似物与白藜芦醇一样具有多种生理药理活性,其中有些化合物的活性、选择性及稳定性均要强于白藜芦醇,故备受关注,成为近些年的研究热点。

关 键 词:白藜芦醇  衍生物  类似物  药理活性  构效关系
文章编号:1001-5094(2006)04-0145-06
收稿时间:2005-10-18
修稿时间:2005-10-18

Advances in the Research of Resveratrol Derivatives and Analogues
CHEN Guo-liang,GENG Chun-mei,LIU Xiang-yong. Advances in the Research of Resveratrol Derivatives and Analogues[J]. Progress in Pharmaceutical Sciences, 2006, 30(4): 145-150
Authors:CHEN Guo-liang  GENG Chun-mei  LIU Xiang-yong
Affiliation:School of Pharmaceutical Engineering, Shenyang Pharmaceutical University, Shenyang 110016, China
Abstract:
The biological and pharmaceutical activities and the structure-activity relationships of resveratrol derivatives and analogs which including hydroxyl, methyl, ester derivatives and so on were reviewed classifiedly. These compounds have so multiple biological and pharmacological activities as resveratrol, of which some are superior in activity, selectivity and stability to resveratrol and have become a focus of research in recent years.
Keywords:Resvemtrol   Derivative    Analog    Pharmacological activity   Structure-activity relationship
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