PET/CT显像在肝细胞癌患者术后随访中的价值

目的探讨18F氟代脱氧葡萄糖(18F-FDG)PET/CT显像在肝细胞癌(HCC)患者术后随访中的应用价值。方法回顾性分析2011年4月-2016年4月医院PET中心检查的86例疑似HCC术后复发、转移患者的18F-FDG PET/CT显像结果,评价18F-FDG PET/CT对肝癌术后复发、转移的诊断效能。结果全组病例随访13-59个月,经组织病理或临床随访证实52例复发和(或)转移,其中单独肝内复发者27例,单独肝外转移者6例,肝内复发合并肝外转移者19例。以组织病理或临床随访为"金标准",18F-FDG PET/CT诊断HCC术后复发或(和)转移的敏感性为94.23%,特异性为88.24%,准确性为91.86%。结论18F-FDG PET/CT显像对HCC术后复发、转移的检出率较高,便于全面评估患者病情。

Value of PET/CT Imaging in Postoperative Follow-up of Patients with Hepatocellular Carcinoma

Objective To investigate the value of 18F fluorodeoxyglucose (18F-FDG) PET/CT imaging in postoperative follow-up of patients with hepatocellular carcinoma (HCC). Methods The 18F-FDG PET/CT imaging results of 86 patients with suspected recurrence and metastasis of HCC after operation who were examined in PET Center of the hospital during April 2011 to April 2016 were analyzed retrospectively. The diagnostic efficiency of 18F-FDG PET/CT for recurrence and metastasis of HCC after operation was evaluated. Results All cases were followed up for 13-59 months. 52 cases of recurrence and/or metastases were confirmed by histopathology or clinical follow-up. Among them, there were 27 cases with solitary intrahepatic recurrence, 6 cases with solitary extrahepatic metastasis, and 19 cases with intrahepatic recurrence and extrahepatic metastasis. With histopathology or clinical follow-up as the golden standard, the sensitivity, specificity and accuracy of 18F-FDG PET/CT in the diagnosis of recurrence or (and ) metastasis of HCC after operation were 94.23%, 88.24% and 91.86%, respectively. Conclusion The detection rate of recurrence and metastasis of HCC by 18F-FDG PET/CT imaging after operation is high, which is good for comprehensive evaluation of patient's condition.