320排螺旋CT评估升主动脉弹性与冠状动脉狭窄的相关性

目的利用320排螺旋CT评估升主动脉弹性指标与冠状动脉狭窄程度的相关性。方法搜集我院拟诊冠心病并行320排螺旋CT冠状动脉造影138例患者(正常组31例,狭窄组107例),其中狭窄组分为轻度狭窄组及中重度狭窄组,比较不同组间升主动脉弹性指标及与Gensini评分的相关性。结果升主动脉弹性指标[膨胀性(Ao D)及僵硬度(Ao S)]在冠状动脉狭窄组与正常组间及不同狭窄程度组间的弹性指标差异均具有统计学意义(P0.05)。ROC曲线评估Ao D、Ao S预测冠心病的价值,曲线下面积(AUC)分别为0.94、0.89。结论升主动脉弹性与冠状动脉狭窄与否及狭窄程度有密切相关性,有可能可以作为冠心病的独立预测因子。

Evaluation of Correlation between Ascending Aortic Elasticity and Coronary Stenosis by 320 Slice Spiral CT

Objective To evaluate the correlation between the severity of coronary artery stenosis and ascending aortic elasticity by using MDCT.Methods A total of 138 patients with coronary artery disease underwent 320-MDCT coronary angiography. According to the presence of coronary artery stenosis they were divided into coronary stenosis group and no coronary stenosis group, according to the extent of coronary stenosis were divided into mild stenosis and moderate-severe stenosis group; ascending aorta elastic parameters and the Gensini score were compared between different groups.Results The AoD of Coronary stenosis group was significantly lower than that of no stenosis group. AoS and the Gensini score were significantly higher than no stenosis group (P<0.05). Mild group AoD was significantly higher than that of moderate- severe group, AoS and Gensini score were significantly lower than the moderate-severe group(P<0.05). ROC curve was used to evaluate AoD, AoS predicting coronary artery disease and the area under the curve (AUC) was directly 0.94, 0.89.Conclusion The elasticity of ascending aorta is closely related to the extent and extent of coronary stenosis, and may be an independent predictor of coronary artery disease.