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Mammary Cancer in Humans and Mice: A Tutorial for Comparative Pathology. The CD-ROM
Authors:Robert D. Cardiff  Ulrike Wagner  Lothar Henninghausen
Affiliation:(1) Department of Pathology and Center for Comparative Medicine, University of California, Davis, Davis, California, 95616;(2) Laboratory of Genetics and Physiology, National Institute of Diabetes, Digestive and Kidney Diseases, National Institutes of Health, Bethesda, Maryland
Abstract:
This article introduces a CD-ROM containing whole-mount and histological images of normal growth and development of both the mouse mammary gland and the human breast. It also covers nonneoplastic lesions and neoplasias in both species including a catalog of lesions in genetically engineered mice. Instructions, with examples, on techniques such as whole-mount preparation, immunohistochemistry, in situ hybridization, and common histological stains are provided. The images are based on full-scale 1996 × 1640 pixel images at 300 pixels/inch and are annotated. Every genetically engineered model has one or more accompanying citations. Tables are provided for orientation and organization. The CD includes zoom capabilities, a search engine, and a help mode.
Keywords:mouse mammary gland  human breast  oncogenes  breast cancer  CD-ROM  histopathology  ammary development
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