重症肝炎与非重症肝炎原位肝移植术中机体内环境的对比性研究

目的:比较重症肝炎与非重症肝炎在原位肝移植术中血气、生化指标的变化。方法:26例晚期肝病患者,ASAⅢ～Ⅳ级,据病史、临床表现、肝功能等指标分成非重肝组(I,n=15)和重症肝炎组(Ⅱ,n=11),分别在术前、无肝前期、无肝期30、60min、新肝再灌注期5、30min、术毕抽取右侧桡动脉血进行血气分析,测定pH、BE、血Na+、K+、Cl-、Ca2+、葡萄糖、乳酸和HCO3-浓度,并记录患者术中碳酸氢钠、CaCl2、胰岛素的用量。结果:I组pH、BE、HCO3-从无肝期始明显降低,至再灌注5min时为最低,以后逐渐回升;K+浓度从无肝期始升高,至再灌注5min时为最高,以后逐渐下降;血糖、乳酸水平随手术的进行呈升高趋势,术毕时乳酸有所下降。Ⅱ组pH、BE、HCO3-从无肝期始明显降低,新肝期30min时逐渐回升;K+浓度从无肝期始升高,至再灌注30min时逐渐下降;血糖、乳酸水平随手术的进行呈升高趋势。组间比较,II组术前pH、BE、HCO3-明显高于I组,无肝期30min明显低于I组,无肝期60min、新肝再灌注期5min时pH、BE、HCO3-又明显高于I组;Ⅱ组血K+在再灌注期5min时明显高于I组。...

A study to compare the changes of blood gas analysis during operation of orthotopic liver transplantation (OLT) between fulminant hepatic failure (FHF) and non-FHF

Objective To compare the changes of blood gas analysis and electrolytes during operation of orthotopic liver transplantation (OLT) between fulminant hepatic failure (FHF) and non-FHF. Methods Twenty-six patients with end stage liver disease were divided into 2 groups :non-FHF group( I ,n=15 ),FHF group (Ⅱ , n=11 ). Blood samples were drawn out from right radioartery to analyze blood gas and electrolytes at the time of pre-operation, preanhepatic period, 30, 60 min during anhepatic period, 5, 30 min post-rep...