首页 | 本学科首页   官方微博 | 高级检索  
     

临床评分和D-二聚体检查在下肢深静脉血栓中的应用
引用本文:朱力,王建国,刘敏,郭晓娟,郭玉林,郭佑民,王辰. 临床评分和D-二聚体检查在下肢深静脉血栓中的应用[J]. 中华心血管病杂志, 2009, 37(6): 818-822. DOI: 10.3760/cma.j.issn.0253-3758.2009.09.012
作者姓名:朱力  王建国  刘敏  郭晓娟  郭玉林  郭佑民  王辰
作者单位:宁夏医科大学附属医院放射科,银川,750004;深圳市第五人民医院放射科;首都医科大学附属朝阳医院;
基金项目:国家"十一五"科技攻关项目基金资助
摘    要:
Objective To evaluate the value of Wells score or/and D-dimer test on diagnosing or excluding deep venous thrombosis (DVT). Methods Patients with suspected DVT were retrospectively analyzed. All patients underwent clinical assessment, D-dimer assay and bilateral lower extremity eompression sonography within 48 hours of admission. The sensitivity, specificity, positive predictive value (PPV), and negative predictive value (NPV) for diagnosing DVT by Wells score, D-direct test, and combined Wells score and D-dimer were compared. Results A total of 274 patients were analyzed. If low probability was defined as negative and moderate and high probabilities were defined as positive, the sensitivity, specificity, PPV and NPV of the Wells score were 78.4%, 66.1%, 52.3% and 86.6%, respectively. At a cut-off of 500 μg/L, the sensitivity, specificity, PPV and NPV of D-dimer test were 73.9% ,66.1%, 50.8% and 84. 2%, respectively. If low probability and D-dimer < 500 μgL were defined as negative, moderate and high probabilities and D-dimer≥500 μg/L were defined as positive, the sensitivity, specificity, PPV and NPV of the combined Wells score and D-dimer test were 88.3%, 76.8%, 67.1% and 92.5% , respectively. Conclusion For clinical suspected DVT patients, DVT diagnosis could be reliably obtained by combined Wells score and D-dimer test.

关 键 词:静脉血栓形成   D-二聚体检查   诊断   

Value of combined Wells score and D-dimer test on diagnosing patients with deep venous thrombosis
Abstract:
Keywords:Venous thrombosisD-dimer testingDiagnosis
设为首页 | 免责声明 | 关于勤云 | 加入收藏

Copyright©北京勤云科技发展有限公司  京ICP备09084417号