| 131I治疗分化型甲状腺癌转移灶疗效观察 |
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| 引用本文： | 陶新全,王明明. 131I治疗分化型甲状腺癌转移灶疗效观察[J]. 蚌埠医学院学报, 2009, 34(2): 114-116 |
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| 作者姓名： | 陶新全 王明明 |
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| 作者单位： | 安徽医科大学,核医学教研室,安徽,合肥,230032;蚌埠医学院第一附属医院,核医学科,安徽,蚌埠,233004;安徽医科大学,核医学教研室,安徽,合肥,230032 |
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| 摘 要： | 目的：观察分化型甲状腺癌并远处转移患者接受多次大剂量131I治疗的临床效果。方法：45例分化型甲状腺癌并远处转移患者，根据甲状腺癌转移部位给予患者每次口服131I（370—740）×10^7Bq，分2～8次用药，每2次间隔4～12个月；治疗后4—6个月，采用131I全身显像和血清甲状腺球蛋白评价治疗效果。结果：45例中临床治愈15例，有效26例，无效4例。结论：多次131I治疗分化型甲状腺癌转移灶疗效佳，副作用小。
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| 关 键 词： | 甲状腺肿瘤 肿瘤转移 肿瘤/放射疗法 碘同位素/治疗应用 |
Effect of 131I therapy on differentiated thyroid carcinoma metastases |
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| TAO Xin-quan,WANG Ming-ming. Effect of 131I therapy on differentiated thyroid carcinoma metastases[J]. Journal of Bengbu Medical College, 2009, 34(2): 114-116 |
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| Authors: | TAO Xin-quan WANG Ming-ming |
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| Affiliation: | TAO Xin-quan ,WANG Ming-ming (1. Department of Nuclear Medicine ,Anhui Medical University ,Hefei Anhui 230032; 2. Department of Nuclear Medicine, The First Affiliated Hospital of Bengbu Medical College ,Bengbu Anhui 233004, China ) |
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| Abstract: | Objective：To assess the effect of iodine-131 （ 131 I ） therapy on patients with differentiated thyroid carcinoma metastases. Methods ： Forty-five patients with differentiated thyroid carcinoma metastases were treated with 131I, and the dose of 1311 varied according to the site of metastasis（ 370 ×10^7 to 740 × 10^7 ） Bq. The therapy was repeated 2 to 8 times at an interval of 4 to 12 months. The efficacy was assessed 4 - 6 months later with 131I whole body scanning and serum level of thyroglobulin. Results： Of the 45 cases, 15 were cured,26 improved and 4 had no response. Conclusions： The therapy of high doses of 131I is safe and effective for treatment of differentiated thyroid carcinoma metastases with little adverse side-effect. |
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| Keywords: | thyroid neoplasms neoplasm metastasis neoplasms/radiotherapy isotopes/therapeulic apply |
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