胆囊结石并肝硬化患者行腹腔镜与开腹胆囊切除术的对比研究

目的:探讨腹腔镜胆囊切除术(laparoscopic cholecystectomy,LC)治疗胆囊结石合并肝硬化患者的优点、可行性和疗效。方法:胆囊结石合并肝硬化患者72例,随机分成LC组39例和开腹胆囊切除术(open cholecystectomy,OC)组33例,同组按编号、年龄、性别、肝功能分级等收集和分析数据。结果:LC组和OC组平均手术时间分别为(56.0±4.1)min和(70.8±5.2)min(P<0.05),术中平均出血量分别为(97.7±4.03)ml和(133.9±8.64)ml(P<0.05),平均住院时间分别为(6.2±1.9)d和(9.11±2.3)d(P<0.05),手术并发症发生率分别为10.2%(4例)和27.3%(9例)(P<0.05)。结论:胆囊结石合并肝硬化的患者用LC治疗优势明显,与OC相比更加安全可靠。

Comparative study of laparoscopic cholecystectomy and open cholecystectomy for patients with cholelithiasis associated with cirrhosis

Objective:To evaluate the the advantages,feasibility and benefits of laparoscopic cholecystectomy(LC) for patients with cholelithiasis associated with cirrhosis.Methods:Seventy two cases with symptomatic cholelithiasis and cirrhosis were randomly divided into LC group(39 cases) and open cholecystectomy(OC) group(33 cases).The cohorts were well-matched for number,age,sex,child classification.Data of the two groups were collected and analyzed.Results:LC group and the OC group were operative time(56.0±4.1)min and(70.8±5.2)min(P<0.05),bleeding respectively(97.7±4.03)ml and(133.9±8.64)ml(P<0.05),length of hospitalization,respectively(6.2±1.9)d and(9.11±2.3)d(P<0.05),surgical complication rate was 10.2%(4 cases) and 27.3%(9 cases)(P<0.05).Conclusions:Cholelithiasis with cirrhosis to use LC has obvious advantages compared to OC.