A human laboratory study of the effects of quetiapine on subjective intoxication and alcohol craving |
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| Authors: | Lara A. Ray Pauline F. Chin Andia Heydari Karen Miotto |
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| Affiliation: | (1) Department of Psychology, University of California Los Angeles, 1285 Franz Hall, Box 951563, Los Angeles, CA 90095–1563, USA;(2) Department of Psychiatry and Biobehavioral Sciences, University of California Los Angeles, Los Angeles, CA, USA |
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| Abstract: | Rationale The available treatments for alcoholism are only modestly effective, and patients vary widely in their treatment response. Quetiapine, an atypical antipsychotic medication with antagonist activity at D1 and D2, 5-HT1A and 5-HT2A, H1, and α1 and α2 receptors was shown to promote abstinence, reduce drinking days, and reduce heavy drinking days in a 12-week double-blind placebo-controlled trial. |
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