持续性躯体形式疼痛障碍生命质量的相关因素研究

目的探讨持续性躯体形式疼痛障碍（persist somatoform pain disorder，PSPD）患者的生命质量及相关因素。方法采用横断面调查研究，对60例PSPD患者应用健康状况调查问卷（SF-36）评定其生命质量，医疗结局研究用疼痛量表（MOSPM）评定PSPD严重程度，汉密顿抑郁量表（HAMD17），汉密顿焦虑量表（HAMA）评定伴随的情绪状态。结果（1）除精神健康和精力分量表外，SF-36各分量表评分均显著低于普通居民（P〈0．01）；（2）除一般健康状况分量表外，SF-36各分量表评分与MOSPM总分及各因子分均显著负相关，与HAMD17及HAMA总分显著负相关；（3）除一般健康状况分量表外，有抑郁组的SF-36各分量表、躯体健康总评（PCS）及精神健康总评（MCS）分均显著低于无抑郁组（P〈0．01）；（4）多元逐步回归结果，SF-36的PCS与年龄和MOSPM总分相关，MCS则与HAMD总分和MOSPM总分相关。结论PSPD患者的生命质量显著低于普通人群，疼痛症状、抑郁和焦虑情绪与患者的生命质量密切相关，年龄、疼痛、抑郁为PCS和MCS重要影响因素。

A preliminary study of factors of life quality in patients with persist somatoform pain disorder

Objective: To explore the quality of life of patients with persist somatoform pain disorder(PSPD) and its relative factors.Methods: Cross-sectional survey of 60 PSPD patients.All patients were assessed with Short-Form-36 Health Survey(SF-36) for quality of life,Medical Outcomes Study Pain Measurement(MOSPM) for severity of PSPD,Hamilton Depression Scale(HAMD) and Hamilton Anxiety Scale(HAMA) for comorbid mood disorder.Results:(1) Compared with general population,PSPD patients had significantly lower SF-36 scores except Mental Health(MH) and Vitality(VT) subscales(P<0.01);(2) Except General Health(GH),the scores of all other subscales were negatively correlated with the total score and three factor scores of MOSPM,and with total score of HAMD17 and HAMA;(3) Except General Health(GH),all other subscale scores,physical component scale(PCS) and mental component scale(MCS) of SF-36 of PSPD patients with depression were significantly lower than scores of patients without depression(P<0.01);(4) According to multiple linear stepwise regression,PCS of SF-36 was correlated with age and MOSPM total score of PSPD patients,and MCS of SF-36 was correlated with total score of HAMD and MOSPM.Conclusion:Quality of life of PSPD patients was significantly lower than normal population.Pain,depression and anxiety were correlated with quality of life of PSPD patients.Age,pain and depression were important influential factors of PCS and MCS.