| 肠道病毒71型核酸检测在诊断手足口病中的意义 |
| |
| 引用本文： | 谢欣城,张永乐,张思泉,娄国强. 肠道病毒71型核酸检测在诊断手足口病中的意义[J]. 国际流行病学传染病学杂志, 2010, 37(4): 303-305. DOI: 10.3760/cma.j.issn.1673-4149.2010.05.005 |
| |
| 作者姓名： | 谢欣城 张永乐 张思泉 娄国强 |
| |
| 作者单位： | 浙江中医药大学附属第六医院感染科,310014;310014,浙江中医药大学附属第六医院分子诊断实验室; |
| |
| 摘 要： | ![]()
Objective To evaluate the meaning of EV71 viral nucleic acid test in diagnosis of hand-foot-andmouth disease(HFMD). Methods The feces of 132 HFMD patients and 18 non-HFMD patients were tested by real-time fluorescent RT-PCR on the EV71 viral nucleic acid, the consistent of real-time fluorescence RT-PCR results with the clinical diagnosis was analyzed. Results Of the feces in 132 HFMD cases, 85 were EV71 virus positive (64.39%); of the feces in 18 non-HFMD cases, none were EV71 virus positive, there was a statistical difference between the two groups ( x2 = 26.75, P ＜ 0.05). Conclusions The main pathogen of HFMD is EV71, HFMD can be diagnosed when the viral nucleic acid test is positive, but can't be eliminated when the nucleic acid test is negative, diagnosis should be combined with clinical symptoms.
|
| 关 键 词： | 手足口病 病毒核酸 实时荧光RT-PCR |
Significance of EV71 nucleic acid test in the diagnosis of hand-foot-and-moth disease |
| |
| XIE Xin-cheng,ZHANG Yong-le,ZHANG Si-quan,LOU Guo-qiang. Significance of EV71 nucleic acid test in the diagnosis of hand-foot-and-moth disease[J]. International Journal of Epidemiology and Infectious Disease, 2010, 37(4): 303-305. DOI: 10.3760/cma.j.issn.1673-4149.2010.05.005 |
| |
| Authors: | XIE Xin-cheng ZHANG Yong-le ZHANG Si-quan LOU Guo-qiang |
| |
| Abstract: | ![]()
|
| |
| Keywords: | Hand foot and mouth diseaseViral nucleic acidReal-time fluorescence RT-PCR |
|
|
