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浅低温体外循环期间p50与组织氧代谢的变化
引用本文:刘流 周建美. 浅低温体外循环期间p50与组织氧代谢的变化[J]. 湖南医科大学学报, 1999, 24(5): 454-456
作者姓名:刘流 周建美
摘    要:


关 键 词:体外循环 p50 氧代谢 浅低温 GPB

Changes in p50 and oxygen metabolism during mild hypothermia cardiopulmonary bypass]
L Liu,J Zhou,Q Chen. Changes in p50 and oxygen metabolism during mild hypothermia cardiopulmonary bypass][J]. Bulletin of Hunan Medical University, 1999, 24(5): 454-456
Authors:L Liu  J Zhou  Q Chen
Affiliation:Department of Anesthesiology, Second Affiliated Hospital, Hunan Medical University, Changsha 410011.
Abstract:
OBJECTIVE: To study the changes of p50 and oxygen metabolism during mild hypothermia cardiopulmonary bypass, arterial blood lactate(ABL) were measured, arterial and venous blood gas were analysed in 21 patients undergoing cardiac valve replacement. RESULTS: p50, oxygen consumption(VO2), and oxygen extract rate(ERO2) were decreased during hypothermia and increased during rewarming, respectively (P < 0.05 or P < 0.01), while the change of SvO2 was adversed. PvO2 was decreased significantly during rewarming(P < 0.01), and ABL was continuously increased. CONCLUSION: Both reduction in oxygen utilization during hypothermia and relative deficiency of oxygen supply during rewarming cause tissue hypoxia.
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