血脂康对慢性心力衰竭患者心功能、高敏C反应蛋白及血脂的影响

目的探讨血脂康对慢性心力衰竭(CHF)患者的心功能(左室射血分数)、高敏C反应蛋白(hs-CRP)及血脂的影响。方法将65例CHF患者随机分为2组,均予常规治疗,治疗组在此基础上予血脂康口服,治疗前及治疗后1周、2周、4周抽血查血脂及hs-CRP,查心脏彩超等。结果2组治疗后血脂无明显变化,而治疗组治疗1周后hs-CRP即开始降低,心功能开始改善,与治疗前及对照组比较均有显著性差异(P均<0.05)。结论血脂康在早期即可明显降低慢性心力衰竭患者hs-CRP的水平,改善心功能,与血脂TC、LDL-C下降无相关性,说明血脂康治疗心力衰竭是通过调脂以外起作用的,可能对心力衰竭患者的治疗带来益处。

Effect of Xuezhikang on heart function, hs-CRP and blood liquid in patients with chronic heart failure

Objective It is to explore the effect of Xuezhikang on heart function,hs-CRP and blood liquid in patients with chronic heart failure(CHF).Methods 65 patients with CHF were randomly divided into 2 groups and both were treated with normal drugs.The treatment group was given Xuezhikang by oral use on the basis of treatment above.Blood was gotten before treatment and 1,2,4 weeks' after treatment to determine blood liquid and hs-CRP,hearts in the patients were also examined by color ultrasound.Results There was no obvious change of blood liquid after treatment in both groups,but hs-CRP in treatment group began to decrease and the heart function began to be improved after one week's treatment.Compared with that before treatment and in control group,the differences were significant(P<0.05).Conclusion Xuezhikang can low down the level of hs-CRP and improve heart function in the early time in patients with CHF,but the function is not related with blood liquid(TC,LDL-C) decrease.It shows that Xuezhikang has some function on CHF not by improving liquid,so it can bring some benefit for the treatment for CHF.