| 伤必止的皮肤毒性实验研究 |
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| 引用本文： | 莫遗盛,王冬梅,江晓筠,李丽. 伤必止的皮肤毒性实验研究[J]. 海峡药学, 2007, 19(12): 24-25 |
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| 作者姓名： | 莫遗盛 王冬梅 江晓筠 李丽 |
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| 作者单位： | 广西医科大学第三附属医院药剂科,南宁,53003;广西中医学院药理教研室,南宁,530031 |
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| 摘 要： | 目的研究伤必止对动物皮肤的毒性作用。方法对健康家兔进行皮肤急性毒性实验、皮肤刺激性实验,对健康豚鼠进行皮肤过敏实验。结果伤必止对家兔完整及破损皮肤均未引起急性毒性反应和刺激反应,对豚鼠无致敏作用。结论伤必止应用于临床安全、无毒。
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| 关 键 词： | 伤必止 皮肤急性毒性 皮肤刺激性 皮肤过敏性 |
| 文章编号： | 1006-3765（2007）012-0024-02 |
Study on the dermal toxicity of Shangbizhi |
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| MO Yi-sheng,WANG Dong-mei,JIANG Xiao-jun,LI Li. Study on the dermal toxicity of Shangbizhi[J]. Strait Pharmaceutical Journal, 2007, 19(12): 24-25 |
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| Authors: | MO Yi-sheng WANG Dong-mei JIANG Xiao-jun LI Li |
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| Abstract: | OBJECTIVE To study the toxic action of Shangbizhi on animal skin.METHODS Acute dermal toxicity test and dermal irritation test were conducted in healthy rabbits,and dermal sensitivity test was performed in healthy guinea pigs.RESULTS Shangbizhi had no acute toxicity or irritation to the intact or damaged skin of rabbits and was not allergy inducing to the skin of guinea pigs.CONCLUSION Shangbizhi is safe and nontoxic and can be used in clinic practice. |
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| Keywords: | Shangbizhi Dermal toxicity Dermal irritation Dermal sensitivity |
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