高血压患者血细胞聚集和全血粘度的相关性研究

目的　研究原发性高血压患者血液流变学指标和血细胞聚集的变化关系。方法　血液流变学方法检测。结果　高血压患者红细胞聚集指数和低切变率时全血粘性呈正相关 (P<0 .0 1,P<0 .0 5 ) ,伴有血浆粘性、纤维蛋白原水平和红细胞刚性指数增加 (均 P<0 .0 5 ) ,高血压 II期血小板聚集指标 (Pt max,Pt H,Pt K)还和高切变率时血液粘性呈极显著正相关 (P<0 .0 0 1,P<0 .0 5 ,P<0 .0 0 1)。结论　在对高血压的治疗中 ,应密切注意血小板聚集和全血粘性二者关系的动态变化。

Investigation of Correlation Between Blood Cell Aggregation and Blood Viscosity in Patients with Hypertension

Objective Correlation between blood cell aggregation and blood viscosity was studied in 40 cases essential hypertension(EH). Method Methods of hemorheology. Results ① Aggregative index of erythrocyte was positively correlated with blood viscosity in low shearing rate(P<0.01,P<0.05) and plasmatic viscosity and levels of plasmatic fibrinogen and rigid index of erythrocyte markedly increased (P<0.05,respectivily) in phase I and II hypertension. ② Parameters of platelet aggregation (Pt max, Pt H, Pt K) were positively correlated with blood viscosity in high shearing rate(P<0.001,P<0.05,P<0.001) in phase II hypertension. Conclusion Attention should be paid to the changes of platelet aggregation and blood viscosity in treatment of hypertension.