Comparative analysis of antimicrobial action of polyhexametylenguanide hydrochloride (Biopag) and chlorhexidine bigluconate upon potential infectious agent of suppurative-inflammatory diseases of maxillo-facial region and neck

Sensitivity of microflora representatives isolated from inflammatory foci from 40 patients with suppurative-inflammatory diseases of maxillo-facial region and neck to different concentrations of antiseptic preparations of polyhexametylenguanide hydrochloride (Biopag) and chlorhexidine bigluconate was tested. It was determined that 0.05-0.1% solutions of these antiseptics were optimal for these diseases treatment. Biopag had more pronounced fungicidal action, less toxic and more prolonged antimicrobial action and better organoleptic properties when compared with chlorhexidine bigluconate.