| 抑郁症睡眠障碍与血清IL-2及sIL-2R水平的关系 |
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| 引用本文： | 祁富生,贾福军,郭新胜. 抑郁症睡眠障碍与血清IL-2及sIL-2R水平的关系[J]. 神经疾病与精神卫生, 2003, 3(5): 342-343 |
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| 作者姓名： | 祁富生 贾福军 郭新胜 |
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| 作者单位： | 453002,新乡医学院第二附属医院;453002,新乡医学院第二附属医院;453002,新乡医学院第二附属医院 |
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| 基金项目： | 河南省教育厅立项课题(20013200021) |
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| 摘 要： | 目的探讨IL-2、sIL-2R与抑郁症睡眠障碍的关系.方法采用酶联免疫吸附法(ELSIA)检测35例抑郁症和30名健康对照的血浆IL-2、sIL-2R水平.结果抑郁症组IL-2水平低于对照组(P＜0.05),且IL-2水平与睡眠表浅呈正相关关系(P＜0.05);sIL-2R水平与对照组相比,无明显差异(P＞0.05).结论抑郁症患者的睡眠表浅可能与血浆IL-2水平降低有关.
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| 关 键 词： | 抑郁症 睡眠障碍 白介素2 可溶性白介素2受体 |
| 文章编号： | 1009-6574(2003)05-0342-02 |
| 修稿时间： | 2003-03-28 |
Relationships between Serum Levels of IL-2 and sIL-2R with Sleep Disorder in Depressive |
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| Qi Fusheng,Jia Fujun,Guo Xinsheng.. Relationships between Serum Levels of IL-2 and sIL-2R with Sleep Disorder in Depressive[J]. Nervous Diseases and Mental Health, 2003, 3(5): 342-343 |
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| Authors: | Qi Fusheng Jia Fujun Guo Xinsheng. |
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| Abstract: | Objective To explore the relationships between interleukin -2 (IL -2) and sIL -2R with sleep disorder in depressive. Methods Plasma levels of IL - 2 and sIL-2R in 35 cases of depressive and 30 controls were measured by enzyme linked immunosorbent assay (ELISA). Results IL - 2 levels in depressive group were lower then those in control group (P < 0. 05) , and their IL- 2 levels have positive relations with sleep situation (P < 0. 05) , There was no difference between the two groups (P > 0. 05) in sIL-2R level. Conclusions The sleep situation in depression was related with the plasma level of IL-2. |
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| Keywords: | Depressive Sleep disorder Interleukin-2 Soluble interleukin-2 receptor |
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