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TCR-mediated activation of allergen-specific CD45RO(+) memory T lymphocytes results in down-regulation of cell-surface CXCR4 expression and a strongly reduced capacity to migrate in response to stromal cell-derived factor-1.
Authors:C Abbal  P Jourdan  T Hori  J Bousquet  H Yssel  J Pène
Affiliation:INSERM U454, H?pital Arnaud de Villeneuve, 375 Avenue Doyen Gaston Giraud, 34295 Montpellier Cedex 5, France.
Abstract:
Keywords:allergy   CD45RO   chemokine receptors   CXCR4   IL-4   stromal cell-derived factor   T cell activation
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