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Preoperative home elemental enteral nutrition in complicated Crohn's disease
Authors:G K Blair  M Yaman  D E Wesson
Affiliation:1. Department of Dietetics, National University Hospital, Singapore;2. Department of Pediatrics, Faculty of Medicine, University Malaya, Kuala Lumpur, Malaysia;3. Pediatrics and Child Health Research Group, University Malaya, Kuala Lumpur, Malaysia;4. Department of Pediatrics, Khoo Teck Puat-National University Children''s Medical Institute, National University Hospital, Singapore;5. Yong Loo Lin School of Medicine, National University of Singapore, Singapore;1. Evidence Based Medicine Center, School of Basic Medical Sciences, Lanzhou University, Lanzhou, Gansu, PR China;2. Key Laboratory of Evidence Based Medicine and Knowledge Translation of Gansu Province, Lanzhou, Gansu, PR China;3. School of the Second Clinical Medicine, Lanzhou University, Lanzhou, Gansu, PR China;4. Evidence Based Social Science Research Center, School of Public Health, Lanzhou University, Lanzhou, Gansu, PR China;5. Department of Traditional Chinese Medicine, School of the First Clinical Medicine, Lanzhou University, Lanzhou, Gansu, PR China
Abstract:
Home elemental nutrition (HEN) was used in 11 children and adolescents with complicated Crohn's disease to relieve their immediate symptoms and make them more fit for definitive surgery. HEN resulted in symptomatic relief, weight gain from a mean of 47 to 53 kg (P less than .001) and reduction in prednisone requirements from a mean daily dose of 30 to 6 mg (P less than .001). The seven patients who subsequently underwent definitive bowel resection suffered no surgical complications. HEN was well tolerated by all patients. HEN offers a simple, safe, and cost effective means of preparing patients with complicated Crohn's disease for operation.
Keywords:
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