| 阿立哌唑与氯氮平治疗精神分裂症对照研究 |
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| 引用本文： | 王刚平,颉瑞,裴根祥,张永录.阿立哌唑与氯氮平治疗精神分裂症对照研究[J].临床精神医学杂志,2006,16(1):44-45. |
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| 作者姓名： | 王刚平 颉瑞 裴根祥 张永录 |
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| 作者单位： | 741000,甘肃天水市精神病医院 |
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| 摘 要： | 目的:探讨阿立哌唑与氯氮平对首发精神分裂症患者的临床疗效及安全性。方法:对64例精神分裂症患者随机分为两组,分别给予阿立哌唑与氯氮平治疗,疗程8周。用阳性与阴性症状量表(PANSS)和副反应量表(TESS)评定疗效和不良反应。结果:两组疗效差异无显著性(P>0.05),阿立哌唑不良反应显著少于氯氮平(P<0.01)。结论:阿立哌唑是一种安全有效的抗精神病药。
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| 关 键 词： | 精神分裂症 阿立哌唑 氯氮平 |
| 文章编号： | 1005-3220（2006）01-0044-02 |
| 收稿时间： | 2005-03-28 |
| 修稿时间： | 2005年3月28日 |
Comparative study between aripiprazole and clozapine in the treatment of patients with schizophrenia |
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| WANG Gang-ping,XIE Rui,PEI Gen-xiang,ZHANG Yong-lu.Comparative study between aripiprazole and clozapine in the treatment of patients with schizophrenia[J].Journal of Clinical Psychological Medicine,2006,16(1):44-45. |
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| Authors: | WANG Gang-ping XIE Rui PEI Gen-xiang ZHANG Yong-lu |
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| Institution: | Tianshui Mental Hospital, Tianshui 741000, China |
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| Abstract: | Objective:To detect the clinical efficacy and side effect of aripiprazole and clozapine in the treatment of first episode schizophrenic patients. Method:64 schizophrenic inpatients have been divided into aripiprazole group and clozapine group randomly to treat for 8 weeks.Positive and negative symptom scale(PANSS) and treatment emergent symptom scale(TESS) were used to evaluate the efficacy and side effects respectively. Results:There were no significant difference in efficacy between two groups.Aripiprazole had less side effects than clozapine. Conclusion:Aripiprazole is a safe and effective antipsychotic drug. |
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| Keywords: | schizophrenia aripiprazole clozapine[FQ)] |
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