过敏原检测在儿童反复哮喘中的临床应用

目的探讨过敏原检测在反复哮喘儿童中的应用及临床意义。方法回顾性分析该院2013年2月至2015年2月收治的524例反复哮喘患儿的临床资料,根据年龄分为3组:婴儿组(0~1岁)250例,幼儿组(1~3岁)150例,儿童组(≥3岁)124例。3组患儿均予以过敏原检测,比较其过敏原阳性率及过敏源的分布情况。结果患儿过敏原检测总阳性率为39.69%(208/524),其中儿童组过敏原阳性率(66.13%)最高,婴儿组(24.00%)最低,3组过敏原阳性率比较差异有统计学意义(P0.05)。牛奶、户尘螨及猫毛皮屑过敏原的阳性率位于前3位,且儿童组户尘螨和屋尘阳性率最高,婴儿组最低,3组比较差异有统计学意义(P0.05)。结论过敏原检测对反复哮喘儿童尤为重要,不仅可以快速找到哮喘的病因,而且能够更早地识别可能发展为哮喘的儿童,为儿童哮喘的早期干预提供依据。

Clinical application of allergen detection in recurrent childhood asthma

Objective To explore the application of allergen detection in children with recurrent asthma and its clinical signifi‐cance .Methods The clinical data of 524 cases of children with recurrent asthma in this hospital ,from February 2013 to February 2015 ,were retrospectively analysed .According to age ,these children with recurrent asthma were divided into three groups:250 ca‐ses were enrolled into infants group(0- <1 years old) ,150 cases enrolled into cheepers group(1- <3 years old) ,124 cases were enrolled in children group (≥3 years old) .Children in the three groups were treated with allergen detection ,and positive rates and distribution of allergens were compared among three groups .Results The total positive rate of allergen detection was 39 .69%(208/524) .The positive rate of allergen detection was the highest in children group(66 .13% ) ,and the lowest in infants group (24 .00% ) ,and there were statistically significant differences in the positive rates among the three groups(P<0 .05) .The top 3 common allergens were milk ,household dust mite and cat dander .The positive rates of household dust mite and house dust were the highest in children group ,but lowest in infants group ,there were statistically significant differences in the positive rate among the three groups(P<0 .05) .Conclusion Allergen detection is particularly important for children with recurrent asthma ,which not only could quickly find the etiology of asthma and identify children who are susceptible to asthma ,but also provide references for early intervention in childhood asthma .