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大蒜新素对饲高胆固醇饮食的鹌鹑动脉及肝脏cAMP水平的影响
引用本文:钱晓涛,黄文兴. 大蒜新素对饲高胆固醇饮食的鹌鹑动脉及肝脏cAMP水平的影响[J]. 山东大学学报(医学版), 1985, 0(2)
作者姓名:钱晓涛  黄文兴
作者单位:山东医学院药理学教研室,山东医学院药理学教研室
摘    要:
持续用高胆固醇饲料喂养鹌鹑45天,使患高胆固醇血症,动脉及肝脏的cAMP水平显著降低。用50mg/kg/d大蒜新素灌胃,可有效地防止高胆固醇饮食引起的鹌鹑血浆总胆固醇水平的急骤升高,并可维持动脉及肝脏的cAMP水平接近正常对照组。

关 键 词:大蒜新素  胆固醇  血胆甾醇过多症  环磷酸腺苷

EFFECT OF ALLITRIDI ON cAMP LEVEL OF AORTA AND LIVER OF KOREAN QUAIL FED WITH CHOLESTEROL
Qian Xiaotao Huang Wenxing. EFFECT OF ALLITRIDI ON cAMP LEVEL OF AORTA AND LIVER OF KOREAN QUAIL FED WITH CHOLESTEROL[J]. Journal of Shandong University:Health Sciences, 1985, 0(2)
Authors:Qian Xiaotao Huang Wenxing
Abstract:
Studies have been performed on groups of Korean quail 6 weeks of age, one of which had been fed with hypercholesterol diet(1% cholesterol), another hypercholesterol diet and Allitridi (50mg/kg wt./day p. o), the third stock diet. Hypercholestermia and lower cAMP level of aorta and liver of quail had been produced by feding cholesterol for 15, 30, 45 days, Allitridi has significantly prevented the increase of plasma cholesterol level (p<0.01) and maintained the cAMP level when compared to normal controls.
Keywords:Allitridi  Cholesterol  Hypercholesteremia  Cyclic AMP  
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