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| ICSI- ET黄体中期应用GnRHa对妊娠结局的影响 | |
| 引用本文： | 周寒鹰,师娟子,薛侠,孟彬,于玲,田莉,柏海燕,王辉. ICSI- ET黄体中期应用GnRHa对妊娠结局的影响[J]. 实用临床医药杂志, 2011, 15(15) |
| 作者姓名： | 周寒鹰 师娟子 薛侠 孟彬 于玲 田莉 柏海燕 王辉 |
| 作者单位： | 陕西省妇幼保健院生殖中心,陕西西安,710003 |
| 基金项目： | 陕西省科技厅科技攻关项目，陕西省卫生厅项目 |
| 摘 要： | 目的 单精子卵胞浆内显微注射-胚胎移植周期中黄体中期应用促性腺素释放激素激动剂(GnRHa)是否提高临床妊娠率.方法 300个单精于卵胞浆内显微注射-胚胎移植周期的病例,随机分为实验组及对照组,移植日为单数日做为实验组,移植后3d单次皮下注射GnRHa 0.1 mg,对照组不予以注射GnRHa,比较2组患者在GnRHa用药前后血清激素水平、种植率及临床妊娠率的变化.结果 实验组临床妊娠率为51.25%,对照组为45.00%；GnRHa组和对照组激素水平、种植率及临床妊娠率相当.结论 单精子卵胞浆内显微注射-胚胎移植周期中黄体中期应用GnRHa,其种植率、临床妊娠率、流产率、活胎出生率、卵巢过度刺激综合征(OHSS)没有显著改善. |
| 关 键 词： | 单精子卵胞浆内显微注射 胚胎移植 GnRHa 种植率 临床妊娠率 活胎出生率 |
Effect of luteal- phase gonadotropin- releasing hormone agonist administration on clinical pregnancy rate after intracytoplasmic sperm injection |
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| ZHOU Han-ying,SHI Juan-zi,XUE Xia,MENG Bin,YU Lin,TIAN Li,BO Hai-yan,WANG Hui. Effect of luteal- phase gonadotropin- releasing hormone agonist administration on clinical pregnancy rate after intracytoplasmic sperm injection[J]. Journal of Clinical Medicine in Practice, 2011, 15(15) | |
| Authors: | ZHOU Han-ying SHI Juan-zi XUE Xia MENG Bin YU Lin TIAN Li BO Hai-yan WANG Hui |
| Abstract: | Objective To evaluate the effect of gonadotropin-releasing hormone(GnRH) agonist,administered in the luteal-phase,on intracy to plasmic sperm injection(ICSI) outcome.Methods 300 intracytoplasmic sperm microinjection-embryo transfer cases were divided into experimental and control groups,transplantation at single days as the experimental group.3 days after transplantation,GnRHa group was given a single subcutaneous injection of 0.1 mg of GnRHa,control group did not.Serum hormone levels,implantation rate and ... |
| Keywords: | intracytoplasmic sperm injection embryo transplantation GnRH agonist implantation rate clinical pregnancy rate live birth rates |
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