阻塞性睡眠呼吸暂停低通气综合征患者生活质量分析

目的：分析阻塞性睡眠呼吸暂停低通气综合征（obstructive sleep apnea hypopnea syndrome，OSAHS）患者生活质量及其相关影响因素。方法：采用Calgary睡眠呼吸暂停疾病特异性生活质量调查表和Epworth嗜睡量表（Epworth sleepiness scale，ESS）评价OSAHS患者和单纯鼾症患者的生活质量和白天过度嗜睡（excessive daytime sleepiness，EDS），比较OSAHS患者与单纯鼾症患者之间各指标的差异，用pearson相关分析OSAHS患者Calgary生活质量指数（the Calgary sleep apnea quality of life index, SAQLI）与体重指数、颈围、腹围、睡眠结构、呼吸紊乱、EDS等指标的相关性，采用多元逐步回归分析探讨OSAHS患者生活质量的影响因素。结果：OSAHS患者和单纯鼾症患者的SAQLI等各指标之间存在差异，OSAHS患者的生活质量与体重指数、颈围、腹围、睡眠结构、呼吸紊乱等指标无相关，与EDS相关。多元逐步回归分析显示EDS是OSAHS患者生活质量的独立预测因素。结论：OSAHS患者的生活质量较单纯鼾症患者明显下降，EDS是OSAHS患者生活质量的重要影响因素。

Health-related quality of life in patients with obstructive sleep apnea hypopnea syndrome

Objective: To evaluate the health-related quality of life in patients with obstructive sleep apnea hypopnea syndrome and the influencing factors.Methods: The Calgary questionnaire for health-related quality of life of patients with sleep apnea and the Epworth sleepiness scale(ESS) were used to evaluate the quality of life and excessive daytime sleepiness(EDS) in OSAHS patients and simple snoring patients.The Pearson correlation and stepwise multiple regression analysis were used to analyze the correlation between the SAQLI and body mass index(BMI),neck collar,abdomen circumference,sleep architecture,respiratory disturbances and EDS.Results: There was a difference in each aspect between OSAHS patients and simple snoring patients.The SAQLI was significantly correlated with EDS.Conclusions: The health-related quality of life in patients with OSAHS is reduced.EDS is an important influencing factor for the health-related quality of life in patients with OSAHS.