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27例嗜酸粒细胞性胃肠炎临床诊治分析
引用本文:谢聪颖,谭诗云,张军,黄平晓.27例嗜酸粒细胞性胃肠炎临床诊治分析[J].胃肠病学和肝病学杂志,2010,19(3).
作者姓名:谢聪颖  谭诗云  张军  黄平晓
作者单位:武汉大学人民医院消化科,湖北,武汉,430060
摘    要:目的探讨嗜酸粒细胞性胃肠炎(eosinophilic gastroenteritis,EG)临床表现、内镜、病理特点及诊治方法。方法回顾性分析我院2003年1月~2008年9月的27例住院EG患者的临床资料,对其临床分型及诊治方法进行分析。结果本组27例EG中黏膜型17例、浆膜型4例、黏膜浆膜混合型5例及黏膜肌层混合型1例。85.19%的患者以腹痛为首发症状,内镜检查病变多分布在胃窦、十二指肠降部和回盲部。活体组织病理学检查或腹水细胞学发现大量嗜酸粒细胞浸润。予以糖皮质激素或抗组胺类药物,腹痛症状均在1周内缓解。结论EG主要发生于20~50岁青中年患者,以黏膜型最常见,多以腹痛为主要症状且常规镇痛药物疗效不佳,内镜活体组织病理学检查或腹水细胞学检查有助于明确诊断。糖皮质激素治疗疗效显著。

关 键 词:嗜酸粒细胞性胃肠炎  腹痛  内镜

Diagnosis and treatment of 27 patients with eosinophilic gastroenteritis
XIE Congying,TAN Shiyun,ZHANG Jun,HUANG Pingxiao.Diagnosis and treatment of 27 patients with eosinophilic gastroenteritis[J].Chinese Journal of Gastroenterology and Hepatology,2010,19(3).
Authors:XIE Congying  TAN Shiyun  ZHANG Jun  HUANG Pingxiao
Institution:XIE Congying,TAN Shiyun,ZHANG Jun,HUANG PingxiaoDepartment of Gastroenterology,Renmin Hospital of Wuhan University,Wuhan 430060,China
Abstract:Objective To investigate the clinical,endoscopic and pathological characteristics,diagnosis and therapy of eosinophilic gastroenteritis(EG).Methods The clinical data of 27 patients with EG in our hospital from January 2003 to September 2008 were analyzed retrospectively in clinical types,diagnosis and treatment.Results There were 17 mucosal EG,4 serosal EG and 6 combination EG.The major clinic sign of 85.19% patients was abdominal pain.The lesions in endoscopy were mostly located at antrum,descending part o...
Keywords:Eosinophilic gastroenteritis  Abdominal pain  Endoscopy  
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