固肾育胎贴外敷三阴交治疗胎动不安临床研究

目的观察固肾育胎贴外敷三阴交治疗胎动不安临床疗效。方法选择胎动不安患者216例,随机分为治疗组(108例)和对照组(108例)。2组均予中医辨证论治、黄体酮软胶囊治疗,治疗组同时予固肾育胎贴外敷三阴交。2组均以5 d为1个疗程,共治疗3个疗程。疗程结束观察2组患者阴道出血、下腹坠痛、腰酸痛、恶心呕吐等症状改善情况,测定子宫动脉搏动指数(PI)、子宫动脉血流阻力指数(RI)等变化。结果治疗组总有效率为97.22%(105/108),对照组总有效率为90.74%(98/108),2组比较差异有统计学意义(P0.05)。治疗组治疗后症状总积分改善明显,优于对照组(P0.01)。治疗后有效组和发展为流产的无效组B超子宫PI、RI值比较差异均有统计学意义(P0.01)。结论在中医辨证论治、黄体酮软胶囊基础上联合中药固肾育胎贴外敷三阴交治疗胎动不安可明显提高疗效;子宫动脉上行支的PI、RI值可作为妊娠是否存活的辅助判断指标。

Clinical Study on Sanyinjiao Acupoint Sticking with Gushen Yutai Tie in Treatment of Threatened Abortion

Objective To observe the clinical efficacy of Sanyinjiao acupoint sticking with Gushen Yutai Tie on threatened abortion. Methods A total of 216 women diagnosed with threatened abortion were randomly assigned to trial group （108 cases） and control group （108 cases）. Both groups were treated with TCM syndrome differentiation treatment and progesterone soft capsule, and the trial group was treated with Gushen Yutai Tie acupoint sticking at Sanyinjiao （SP6） additionally. One treatment course was five days, and both groups were treated for three courses. Vaginal bleeding and lower abdominal pain, lumbar pain, nausea and vomiting were observed, pulsatility index （PI） and resistance index （RI） of the uterine artery were detected after treatment. Results The total effective rate in the trial group was 97.22% （105/108）, which was significantly higher than that of 90.74% （98/108） in the control group （P〈0.05）. Symptom scores in the trial group were also significantly higher than those in the control group （P〈0.01）. PI and RI in the ineffective （pregnancy failure） group were much lower than that of effective （threatened abortions with normal outcome） group （P〈0.01）. Conclusion The treatment that Gushen Yutai Tie acupoint sticking at Sanyinjiao combined with TCM syndrome differentiation and progesterone soft capsule had a better effect to improve pregnancy success rate in threatened abortion. PI and RI in uterine artery could be used to evaluate the outcome of pregnancy.