臭氧联合局部用药治疗早孕合并阴道炎疗效观察

目的：探索臭氧联合局部用药治疗宫内早孕合并阴道炎效果观察,避免术后并发症的发生.方法：将2011年6月至2013年3月来中心妇科门诊自愿要求终止妊娠的女性256例,年龄在25~40岁;B超声确诊为宫内早孕,实验室阴道分泌物检测确诊为外阴阴道假丝酵母菌病.随机分成两组,治疗组128例,采用臭氧液（连续冲洗3d,每次3min）加克霉唑阴道片500mg（阴道上药2次）.对照组128例,克霉唑阴道片500mg（隔日阴道上药共2次）.停药3d复查.结果：治疗组与对照组的治愈率分别为 87.50%和58.59%,好转率分别为12.50 %和 31.25%.两组比较差异显著,具有统计学意义（P＜0.01）.臭氧治疗组无不良反应.结论：臭氧联合局部用药治疗宫内早孕合并外阴阴道假丝酵母菌病安全、有效,并能彻底治愈,减少术后并发症的发生,提高女性的生活质量,值得临床应用.

Ozone gynecologic therapy combined with topical use of medicine in treatment of early intrauterine pregnancy complicated with colpitis

Objectives： To investigate the effectiveness of ozone gynecologic therapy combined with topical use of medicine in treatment of early intrauterine pregnancy complicated with colpitis. Method： 256 female aged 25 to 40 who came to the Central Gynecological Clinic during June 2011 and March 2013 to terminate pregnancy were the research subjects. They were diagnosed as early intrauterine pregnancy by B ultrasound. Tests of vaginal secretions showed that they were infected by vulvovaginal candidiasis. They were randomly divided into 2 groups （ 128 in each group）. The treatment group was treated with ozone solution （flush for3 consecutive days, 3 minutes each time） and 500mg clotrimazole vaginal tablets （ twice on vagina）. The control group was treated with only 500mg clotrimazole vaginal tablets （twice every other day on vagina）. They were reviewed three days after terminating the drug. Results： The cure rate was 87.50% in the treatment group, and 58.59% in the control group. The improvement rate was 12. 50% in the treatment group, and 31.25% in the control group. The differences were significant （ P 〈 0. 01 ）. No side effects were found in the treatment group. Conclusion： The combination of ozone gynecologic therapy and topical use of medicine in treatment of early intrauterine pregnancy and vulvovaginal candidiasis is safe and effective. It can completely cure the disease, reduce the occurrence rate of postoperative complications, and im- prove the quality of life for women. It is worthy of clinical application.