通前络汤治疗60例慢性前列腺炎随机对照临床研究

目的：评价通前络汤治疗慢性前列腺炎气滞血瘀证的临床疗效.方法：采用随机、对照临床试验研究方法,通过前列腺液（EPS）常规、美国国立卫生研究院慢性前列腺炎症状评分（NIH-CPSI）及中医临床症状表现,筛选出120例慢性前列腺炎气滞血瘀证患者,随机分为治疗组（ 60例,脱落1例）和对照组（60例,脱落6例）.治疗组服用通前络汤免煎颗粒,早晚各1袋,温水冲服,疗程4周.对照组口服前列欣胶囊,6粒/次,每天3次,疗程4周.所有患者均行入组时、治疗第2周、第4周和第8周访视并行NIH-CPSI评分.结果：治疗组痊愈5例（8.47%）,显效19例（32.20%）,有效28（47.46%）总有效率88.14%.对照组痊愈3例（5.56%）,显效13例（24.07%）,有效22例（40.74%）,总有效率70.37%.两组治疗前后NIH-CPSI积分的自身对比差异均有显著性（P〈0.01）;组间比较,治疗组较对照组第4周和第8周NIH-CPSI总分、疼痛和生活质量评分差异均有显著性（P〈0.05）.结论：通前络汤通过缓解疼痛不适症状和改善患者的生活质量可以有效的治疗慢性前列腺炎.

Effect of dredging prostate collaterals decoction in the treatment of achronic prostatitis

Objectives： To evaluate the efficacy of dredging prostate collaterals decoction in the treatment of stagnation of qi and blood caused by prostatitis. Method： Adopting a clinical randomized clincial, 120 prostatitis patients with qi and blood stagnation were recruited by Expressed Prostate Secretion （EPS） examination and the U. S. National Institute Health - Chronic Prostatitis Symptom Index （ NIH - CPSI） evaluation. The subjects were randomly divided into the treatment group, with 60 cases and 1 missing one and the control group, with 60 cases and 6 missing cases. In the treatment group, the patients were administered with the dredging prostate collaterals decoction every morning and evening for a course of 4 weeks. In the control group, the patients took 6 tablets of QIAN Liexin Capsule three times/d in the course of 4 weeks. At Week 2, Week 4 and Week 8, the efficacy was evaluated by N IH- CPSI. Results： In the treatment group, 5 cases were cured （8.47%）, 19 cases showed effectiveness （32.20%）, 28 cases were valid （47.46%）, with the total efficiency of 88. 14%. In the control group, 3 patients were cured （5.56%）, 13 cases were effective （24. 07% ）, 22 cases showed efficacy （40. 74% ）, with the total efficiency 70. 37%. There was significant difference in NIH - CPSI value between pre - treatment and post - treatment in both groups （P 〈 0. 01 ）. The NIH - CPSI, pain index and life quality index had significant difference between the two groups at Week 4 and Week 8 （ P 〈 0.05 ）. Conelusion： Dredging prostate collaterals decoction is effective in the treatment of chronic prostatitis It can effectively relieve pain and improve the patients＇ life quality.