神经康复治疗在多发性硬化缓解期的疗效观察

目的探讨针刺等神经康复治疗对多发性硬化缓解期患者的临床治疗效果。方法将36例患者分为观察组19例和对照组17例。对照组患者给予糖皮质激素、免疫抑制剂等常规治疗并进行日常生活训练,观察组患者在此治疗基础上早期使用针刺治疗,观察2组的临床疗效,并于治疗前及治疗2、4周后进行扩展型残疾状态量表(EDSS)和疲劳严重度量表(FSS)评分。结果观察组患者治疗有效率高于对照组,差异有统计学意义(χ2=5.573,P<0.05)。治疗2周后观察组患者EDSS评分较对照组显著下降,差异有统计学意义(P<0.05),且观察组患者治疗后EDSS评分较治疗前显著下降,差异有统计学意义(P<0.05);治疗4周后观察组患者EDSS评分较对照组亦显著下降,差异有统计学意义(P<0.05),且较治疗前显著下降,差异有统计学意义(P<0.01),对照组患者治疗4周后EDSS评分较治疗前亦显著下降,差异有统计学意义(P<0.05)。治疗2周后观察组患者FSS评分与对照组比较差异无统计学意义(P>0.05),2组患者治疗后FSS评分较治疗前有所下降,但差异无统计学意义(P>0.05);治疗4周后观察组患者FSS评分较对照组显著下降,差异有统计学意义(P<0.05),且观察组患者治疗后FSS评分较治疗前显著下降,差异有统计学意义(P<0.05),但对照组患者治疗4周后FSS评分与治疗前比较差异无统计学意义(P>0.05)。结论神经康复治疗可有效提高多发性硬化缓解期患者的治疗效果,并能改善EDSS和FSS评分。

Efficacy of neurological rehabilitation in multiple sclerosis remission

Objective To explore clinical efficacy of acupuncture rehabilitation in the multiple sclerosis remission. Methods Thirty-six patients were divided into observation group（ 19 cases） and control group（ 17 cases）. The control group accepted conventional treatment such as glueocorticoids, immunosuppressant, and the training of daily life, while observation group accepted the early use of acupuncture treatment on the basis. The clinical efficacy and expanded disability status scale （EDSS） ,fatigue severity scale（FSS） scores before treatment and two weeks,four weeks after treatment were observed. Results The therapy efficiency of the observation group was higher than that of the control group, there was a statistically significant difference （χ2 = 5. 573,P 〈 0.05 ）. After two weeks of treatment, EDSS score of the observation group significantly decreased than the control group （ P 〈 0. 05 ）, and also decreased than before treatment （ P 〈 0.05 ）. After four weeks of treatment, EDSS score of the observation group significantly decreased than the control group （ P 〈 0. 05 ） , and the scores extremely significant decreased than before treatment （P 〈 0.01 ）. EDSS score at four weeks after treatment in the control group also appeared significant decrease （P 〈 0.05 ）. After two weeks of treatment,there was not statistically significant in the FSS score between the observation group and the control group（P 〉 0. 05 ） ;the FSS scores in the two groups decreased than before treatment but there was no significant difference（ P 〉 0.05 ）. After four weeks of treatment, FSS score of the observation group decreased than the control group （P 〈 0. 05 ）, and the FSS score significantly decreased than before treatment（ P 〈 0.05 ） ;but there was not statistically significant in the FSS score of the control group between pre-treatment and four weeks after treatment （ P 〉 0. 05 ）. Conclusion Neurological rehabilitation therapy in multiple sclerosis remission can increase efficiency and improve the EDSS and FSS score.