| 对检测纤维蛋白降解产物的两种试剂评价 |
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| 引用本文： | 周雯雯,宋鉴清,丁奇,王金行.对检测纤维蛋白降解产物的两种试剂评价[J].血栓与止血学,2014(4):187-190. |
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| 作者姓名： | 周雯雯 宋鉴清 丁奇 王金行 |
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| 作者单位： | 中国医科大学附属第一医院检验科,沈阳110001 |
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| 摘 要： | 目的对两种纤维蛋白降解产物（FDP）定量检测试剂STA-Liatest FDP（法国STAGO公司）和Nanopia P-FDP（日本Sekisui公司）进行实验性能与临床应用进行评价与比较。方法分别对STA-Liatest FDP和Nanopia PFDP进行重复性、稳定性、线性、检测限、抗生物性干扰及比对实验。结果 STA-Liatest FDP的重复性与稳定性优于Nanopia P-FDP;两种试剂均有较好的线性,STA-Liatest FDP略宽;STA-Liatest FDP灵敏度略低于Nanopia P-FDP;比对实验中两种方法相关性理想。结论两种试剂均具有较高的重复性、稳定性、线性、抗生物性干扰能力及对DIC的诊断效能。两种试剂相比较各有优势,实验室可根据自身具体情况进行选择。
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| 关 键 词： | 纤维蛋白降解产物 试剂 方法学评价 |
Evaluation of Two Fibrin Degradation Products Reagents |
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| Institution: | ZHOU Wen- wen, SONG Jian- qing, DING qi, YANG Zhi- dong (The Clinical Laboratory of the First Hospital Affliliated to China Medical Univerisity, Shenyang, 110001, China) |
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| Abstract: | Objective To evaluate and compare the two kinds of fibrin degradation products（ FDP）quantitative detection reagents,STA-Liatest FDP（ STAGO company in France） and Nanopia P-FDP（ Sekisui company in Japan）. Methods We performed,repeatability,stability,linearity,detection limit,anti-interference tests and comparison study on the two reagents,respectively. Results The STA -Liatest FDP＇s repeatability and stability were better than the Nanopia P-FDP; Two reagents had good linearity,STA -Liatest FDP slightly wider; The STA-Liatest FDP sensitivity was slightly lower than Nanopia P-FDP; in comparison study,relativity of the two reagents was not identical. Conclusion both kinds of reagent have high repeatability,stability,linear,anti-interference tests and efficiency to the diagnosis of DIC. Each reagent has unique virtue,the laboratory may select the fit one according to own demend. |
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| Keywords: | Fibrin degradation products Reagent Methods evaluation |
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