Extramedullary hematopoiesis in the lacrimal gland

A 61-year-old woman who carried the diagnosis of chronic myeloid leukemia developed bilateral upper and lower eyelid edema. Orbital magnetic resonance imaging disclosed grossly enlarged lacrimal glands bilaterally. Biopsy of the right lacrimal gland revealed hematopoietic cells and their precursors, and megakaryocytes, consistent with extramedullary hematopoiesis. Extramedullary hematopoiesis can rarely occur in the lacrimal glands of patients with myeloproliferative diseases.